Authors:

Unfer V., Benvenga S.

Abstract

The physiological mechanisms that are behind recruitment and selection of antral follicles in human ovaries remain incompletely understood. One hypothesis is that the follicle, destined to become dominant in a cohort of growing follicles and which will ovulate at mid-cycle, may contain a greater number of granulosa cells and a higher density of FSH receptors. Thus, the dominant follicle acquires greater responsiveness to FSH in comparison with the remaining preantral follicles that instead undergo atresia.