Publications

This section collects the most significant scientific contents of EGOI-PCOS members concerning the use of inositols alone or in association, both in basic research and for clinical application.

Also, the most relevant and updated literature on diagnosis and therapy of PCOS is gathered.

In particular, this collection includes the most recent original articles, clinical trials, reviews and meta-analyzes on the use of inositols especially in the gynecological, reproductive, metabolic, and endocrine fields.

Manuscripts inserted deal with important issues such as Polycystic Ovary Syndrome (PCOS), metabolic syndrome, insulin resistance, gestational diabetes with its complications, neurological defects for the unborn children linked to the nutritional deficiencies of mothers.

Inositol-resistance: how to deal with it?

Jun 2019

The 30% of PCOS women do not respond to inositol treatment, as their microbiome does not absorb it through the intestine. The association of inositol with a milk protein, alpha-lactalbumin, overcomes these absorption problems, and allows patients to respond to inositol treatment, achieving the goal of pregnancy.

Pregnancy and obesity

Jan 2019

The intervention of Professor Facchinetti on the importance of lifestyle changes, balanced nutrition and exercise in order to counteract obesity and achieve a pregnancy. The need for the integration of those substances, such as inositols, which may improve the clinical picture of insulin-resistance, when the change of lifestyle is not enough.

Drug-induced PCOS

Nov 2018

PCOS may be secondary to taking some medications. Antiepileptics, especially valproate, are among the drugs that may induce PCOS. Herein, the focus on this issue by Professor Kandarakis.