il tango della pcos

Nel 2025 ricorre il 90º anniversario della pubblicazione del report di Irving Freiler Stein
e di Michael Leventhal intitolato“Amenorrea associata a ovaie policistiche”.
Il report “Stein e Leventhal” del 1935 è stato sia fondamentale che rivoluzionario.

The Group

The Experts Group on Inositol in Basic and Clinical Research and on PCOS
(EGOI-PCOS)
brings together several international personalities, researchers and
opinion leaders, skilled in the field of inositol physiology and therapy, with the aim
to discuss and share scientific contents relating to their own expertise in the field.

UPDATE

EGOI joins the Alliance for Health Promotion,
a non-governative organization affiliated with the World Health Organization (WHO)

Mission

The Experts Group on Inositol in Basic and Clinical Research,
and on PCOS (EGOI – PCOS) was conceived to address and clarify
some important issues concerning the physiological role and the hypothetical
use of Inositols in a number of biological and medical fields, including gynecology,
reproduction, cancer, neurology, metabolic and endocrinological disorders.

Publications

This section collects the most significant scientific contents of EGOI members
concerning the use of inositols alone or in association, both in basic research
and for clinical application.

Activities

The most significant activities/events about the use of inositols,
alone or in association, both in basic research and in clinical practice
are reported in this section.

The experts group stats & facts

Experts

Countries

Publications

Recent updates

Inositol-resistance: how to deal with it?

Inositol-resistance: how to deal with it?

The 30% of PCOS women do not respond to inositol treatment, as their microbiome does not absorb it through the intestine. The association of inositol with a milk protein, alpha-lactalbumin, overcomes these absorption problems, and allows patients to respond to inositol treatment, achieving the goal of pregnancy.

Inositol-resistance: how to deal with it?

Pregnancy and obesity

The intervention of Professor Facchinetti on the importance of lifestyle changes, balanced nutrition and exercise in order to counteract obesity and achieve a pregnancy. The need for the integration of those substances, such as inositols, which may improve the clinical picture of insulin-resistance, when the change of lifestyle is not enough.

Inositol-resistance: how to deal with it?

Drug-induced PCOS

PCOS may be secondary to taking some medications. Antiepileptics, especially valproate, are among the drugs that may induce PCOS. Herein, the focus on this issue by Professor Kandarakis.

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